well the skin is an outward reflection of internal health if you don't have good systemic Health your skin is going to reflect that and look poorly so that's why we create this concept of beauty inside and out when that organ doesn't get sufficient blood supply because of the deficiency of nitric oxide you lose hydration you lose collagen you get fine lines and wrinkles and you look old most skin care and beauty products are designed to mask to hide the wrinkles hide the fine lines hide the age spots and the blemishes so we thought well let's do something different let's get to the root cause so as a biochemist and physiologist I certainly know what the cell needs to function properly so we make a topical nitric oxide that overcomes the inability of the blood vessels to make nitric oxide so if your body can't make it we do it for you I like to say we've created a new category in skin care and Beauty that's the first and only topical nitric oxide on the market and it complements anything else you're doing you start with this anything that you apply thereafter whether it's growth factors or peptides or any moisturizing or hydrating cream is just going to work better oh so it helps with absorption into the skin actually penetrates that's amazing see I did not know that learned something every day hi guys today I have a doctor and Nathan Brian in the house and he is a specialist in nitric oxide you know better than anybody else please introduce yourself thanks Jim it's a great pleasure to be with you thanks for being here yeah thanks for the invite so my name is Nathan Brian I'm a nitric oxide biochemist and physiologist I've been in the nitric oxide field for going on 25 years my whole purpose was to really understand how the human body makes nitric oxide What goes wrong in people that can't make it and then how do we fix these underlying problems because today we realize nitric oxide is one of the most important molecules produced in the body wow so I have written a list like what is nitric oxide because just a year ago I had no clue what the heck is nitric oxide so it helps with the high blood pressure you tell me if it's correct right yeah so heart attacks poor circulation lack of energy premature aging cold hands and feet brain fog achy joints high cholesterol immune dysfunction and diabetes is there anything else that I missed erectile dysfunction oh um yeah I guess so okay what is actually nitric oxide actually we have here has we're gonna talk about a little bit later but we do have his products nitric oxide this is a lozenge yeah and this is It's a topical we make nitric oxide products and really what makes us different is if your body can't make nitric oxide and you have all these conditions you just talked about then we have product technology that does it for you and that's what differentiates our product from anything else on the market we can detect we can quantify we can verify nitric oxide coming off that we do it systemically or internally through an orally disintegrating tablet and then we do it topically in our skin care product called in one alone I love this why we need this like why our bodies need us well it's a gas that's produced in the body in fact so it's a naturally produced molecule we're not giving something that the body hasn't seen before but it's a signaling molecule it tells our blood vessels to relax and dilate it modulates inflammation immune dysfunction and oxidative stress the Hallmarks of every chronic disease but it improves blood flow and oxygen delivery okay and so when we look at the function of individual organs tissues and cells these cells and tissues have to get sufficient oxygen they have to get nutrients in order for these cells to do their job so we we make nitric oxide when you take this it dilates the blood vessels it improves oxygen delivery and basically inhibits vascular inflammation the earliest stages of aging and the onset and progression of cardiovascular disease which Remains the number one killer of men and women worldwide so it's really the Holy Grail in anti-aging so if we can make nitric oxide it's the earliest stage in the onset and progression of chronic disease so you see cardiovascular disease Jesus is number one killer for men and women in the United States still despite all the decades and billions of dollars in research it Still Remains the number one kill and for me that's simply unacceptable because we know what causes cardiovascular disease we now have diagnosed it and we know how to fix it so there's no excuses the problem is education and awareness and you made a very good point you know just a year ago you had no idea about nitric oxide and you're you're entrenched in a in a field of aging and anti-aging and healthy skin passionate right now about nitric oxide because I know it works yeah look at my nails look at my nails I never had such a long nails when I started taking this I'm like wow it's crazy I I always had struggle of having like a longer this is my nails no nothing like I was like man it works it makes everything you do work better yeah amazing thank you at what age and I know for women and man nitric oxide actually declines well we if you look at population-based studies we know that you lose about 10 to 12 percent of your endothelial function or your ability to make nitric oxide in the blood vessels per decade and that starts you know late teens early 20s and then this 10 to 12 reduction per decade is what really by the time you're 40 or 50 years old you only have about 50 of the nitric oxide you had when you're younger so our whole thought process why do people why is there an age-dependent reduction in nitric oxide production and if we can prevent that can we prevent age-related disease and so now we know that we can actually reverse that you know we have 50 60 year old people who have the vascular age of the 20 or 30 year old we have 20 or 30 year olds that have vascular age of a 50 60 year old so we now know that we can basically regulate nitric oxide production prevent the age-related decline and prevent age-related disease whether it's you know the aging skin or the Aging heart or the Aging blood vessels low nitric oxide affects aging more like towards the skin um especially in women because most of my followers are in their 50s 60s and they care majority of them of course they care about the body and health but they care about you know aging skin aging how that affects well the skin is an outward reflection of internal health yes so if you don't have good systemic Health your skin is going to reflect that and look poorly so that's why we create this concept of beauty inside and out so let's get to the basics the skin is an organ right it's one of the largest organs I like that because you say it's not the largest because you know it's not the language every does I'm like me yeah that's right yeah so when when that organ doesn't get sufficient blood supply because of the deficiency of nitric oxide then what happened you lose hydration yeah you lose collagen you get fine lines and wrinkles and you look old and then you start developing age spots inflammation acne blemishes the tone texture and Clarity of the skin gets worse so our whole thought process was and you know this because you've been in this business for many years most skin care and beauty products are designed to mask yes to hide the wrinkles hide the fine lines hide the age spots and the blemishes yeah so we thought well let's do something different let's get to the root cause so as a biochemist and physiologist I certainly know what the cell needs to function properly so we make a topical nitric oxide that overcomes the inability of the blood vessels to make nitric oxide so if your body can't make it we do it for you okay and then what does that mean will we get blood supply and oxygen to the skin we improve cellular turnover so we have our own stem cells that actually go and replace dysfunctional cells so we improve cellular turnover we get new cells that are deposited and build a new dermis we improve collagen deposition you improve hydration fine lines and wrinkles disappear in the age spots and blemishes go away and we've got I think five published clinical trials using the serum and those slides that you show at the biohacking conference the differences like insane it's it's incredible when I saw my what especially for the scars it's really I was like so we I like to say we've created a new category in skin care and Beauty yeah it's the first and only topical nitric oxide on the market and it complements anything else you're doing you know you have a great line of products it's not meant to replace yeah anything but you start with this exactly so we apply the nitric oxide we open up the blood vessels we start perfusing the cells of the dermis we improve collagen now anything that you apply thereafter whether it's growth factors or peptides or any moisturizing or hydrating cream is just going to work better oh so it helps with absorption into the skin actually penetrates that's what you say see I did not know that learned something every day my question is which nitric oxide blend is the best because they are they're more nitric oxide on the market and yesterday you say that you have that blend that you have a pattern for that right why this one I will say this is the best because it's you right that's right why why this blend that you have is the best well through 25 years of research and Discovery we've identified a way that makes nitric oxide and we do what's called restorative physiology so we try to recapitulate what the body would normally do and so we we created a whole class a new class of supplements called nitraceuticals and so these are products that I've patented I've trademarked and copyrighted so that it's really a differentiating factor so any product that we bring to Market generates nitric oxide gas and this simple composition of matter that uses really some simple chemistry provides a source of nitric oxide where all the other products on the market are giving your body kind of precursors or substrates and hoping they can inverted to nitric oxide yes but now we understand that the reason people are nitric oxide deficient is they can't convert these products or precursors into nitric oxide so it's like putting gas in a car with a blown up engine what we do is we fix the engine and we provide a source of nitric oxide that your body can make completely different and why is there vitamin C and magnesium well part of what we do is basically generate nitric oxide gas and so there's there's some basic some simple chemistry here so the vitamin C and the magnuscorbate is to do two things number one we need magnesium for the nitric oxide synthase enzyme most Americans are deficient magnesium so it's just a supplemental dose we need to restore the normal function of the enzyme and then two when you make nitric oxide you need to prevent any unwanted chemistry there's what's called nitrogative chemistry that can form some unwanted metabolites it's a vitamin C prevents any Nitro seed of chemistry from occurring in that reaction and then thirdly and perhaps most importantly is that vitamin C actually extends the biological half-life of nitric oxide oh so now once we take it or apply it you basically have an extended release form and there's a certain ratio of what we're using out there and it's in both the topical salmon topical and the fun of the science is fundamental to the what form of vitamin C using here it's VI it's ascorbic acid so we have this is how strong is it well it's 20 in the serum so the the whole point here is when there's a difference in pH of both of these okay there's different components in these so when you dispense these and mix it together the final pH is five and a half to six so we want to mimic normal skin pH okay this is vitamin C and here and this is our well it's not a gas when you mix it together it generates nitric oxide that's oh okay so it's the combination of those that create the magic this thing works I have tried and I just fell in love I know it works it's it's amazing well we've got the you know the state the randomized clinical trolls clinical trials that demonstrate that when you use this in our other clinical trials or using this serum twice a day for 30 days and you know maybe we'll show some before and afters but it's really remarkable and transformative results cool I like the info this is amazing I'm pretty sure all of them are gonna like it okay so how much nitric oxide do we need is there a different dose when we age for example like when you're 35 and 85 is it a different dose that you need Well everybody's different I think our individual demands metabolic demands are different so obviously a 20 year old will probably need less than say a 70 or 80 year old so it's based upon how much nitric oxide your body is normally making then how much do we have to give to supplement the deficits like to say there's two types of people out there there's people like you and I who are healthy and want to stay healthy and not get sick and so our requirements for nitric oxide are going to be much different than somebody to say as cardiovascular disease erectile dysfunction diabetes and high blood pressure that those demands are much different than what our domains allow but fortunately we know how much nitric oxide a normal healthy person makes in 24 hours and we basically dial that into our products so with the lozenge if you if you're like us you're normally healthy and just want to take kind of a preventive or prophylactic daily dose of no then one law isn't just sufficient if you've got someone a day one a day and so that losing is designed to have a resident time of about five to six minutes you put it in your mouth let it dissolve don't chew it don't swallow it but it's generating nitric oxide yes [Laughter] I have a friend he's 28 years old he has a blood clots super young but he got the blood clots of course after vaccine how much of this he will should take you know we've done a lot of Investigations into long covet and those with vaccine injury that have the increased susceptibility of the blood clots and really in those conditions because it's the inflammation of the blood vessels and the activation of the platelets by the spike protein so we have to down regulate those adhesive molecules we have to kind of put the brakes on platelet aggregation so for those the protocol is usually one law isn't here for four to six hours and if the person is taking over their blood thinners how that will work you know there's no contraindications or interactions with any standard medications we've been doing this for 10 or 15 years and we've never seen an interaction but I think obviously you should consult with your physician let them know any new regimen you're going on when you're on any prescription medication the nitric oxide that we deliver is completely safe it's very effective in doing what nitric oxide does great great what are the habits right Rick oxide that's big have bad habits that's what I would like to know at least like a few three four habits if you think you know you know that reduces nitric oxide some of these aren't bad habits right I think people try to do things with good intentions please call for bad coffee's not necessarily bad I mean caffeine is a vasoconstrictor right so it will kind of out-compete the vasodilatory effects of nitric oxide so everything in moderation the main things that contribute to loss of nitric oxide are the use of mouthwash oh this one is cool yeah this is the this is the jaw dropper here yeah that's what I was when I was listening to you when we were at the buy hiking conference I was like what what and this is like the information well not from the sky like he has done research yeah and we've published and other people have published on this if you use mouthwash you eradicate the oral microbiome so the bacteria that live in and on our body are there to do things that we as humans can't do one of those is provide a source of nitric oxide so when we indiscriminately kill the microbiome then we shut down my nitric oxide production blood pressure goes up we lose the protective benefits of exercise and all this is explained by a lack of nitric oxide production is there any particular ingredient like fluoride or just well it's for any it's any antiseptic so it's alcohol based mouthwash okay Listerine scope all the antiseptics chlorhexidine the the prescription medication used for chronic halitosis fluoride is an antiseptic so you have to use toothpaste without any fluoride without a fluoride and fluorides in our drinking water it's everywhere so you've got to eliminate fluoride as from ingestion both through toothpaste and through drinking water the water we bathe in so I encourage people to get a home filtration system that removes the fluoride the chlorine the chloramines all the bad stuff that's in Municipal Water is coconut oil for mouth like okay I think so I mean the short answer is we don't know okay I know we've done all the experiments in the studies using antiseptic mouthwash we put people on the Apple watch for as little as seven days and you know sometimes we see as much as a 20 millimeter increase in blood pressure wow so this is a dramatic effect so I tell people if you're using mouthwash you have to stop get rid of fluoride by fluoride free toothpaste and then limit your exposure to fluorine so if you have a high blood pressure ditch that mouthwash that's right two out of three Americans use mouthwash two out of three Americans have an unsafe elevation but crazy it's not it's not coincidental it's crazy so what else will you say mouthwash fluoride toothpaste what else like one more really bad habit it's antacids oh you know in the terminal step of nitric oxide production in the body we need stomach acid to make nitric oxide and there are over 200 million prescriptions rooting foreign acids every year and now you can buy these over the counter things like Prilosec Prevacid Nexium all of these drugs inhibit stomach acid production they inhibit nitric oxide production and now we know that people who have been on these antacids for three to five years have a 40 higher in of heart attack and stroke up steady up just two days ago revealed that people have been on antacids for four to five years have a 30 percent increase in dementia and then if you go back 10 or 12 years we know that these cause increased in bone fractures because you can't absorb certain minerals and nutrients like B vitamins selenium chromium zinc yeah so these drugs are very very dangerous and they should not be used chronically in fact they were never approved by the FDA to use chronic wow so if you're on antacids you have to absolutely get off of them it's killing people dementia heart attack Strokes bone fractures osteoporosis the list continues wow my sister used why is this amazing amazing so those I mean those are very simple things you can stop doing stop using mouthwash get rid of fluoride get off antacids now your body can actually do what it's designed to do yeah we re-flourish and repopulate the the oral Flora we recreate stomach acid production we're now endogenous systems are able to do their job and make nitric oxide nice so what will be then habits that helps to like boost produce nitric oxide well it's the things we've known for hundreds of years it's a good balanced diet in moderation throw in some more green leafy vegetables moderate physical exercise it stimulates the production of nitric oxide production and then you know 20 or 30 minutes of sunlight a day there's certain wavelengths of life that come from the Sun that will stimulate and release nitric oxide yeah and no sunglasses no sunglasses I mean I think in some in some cases there's certain wavelengths of what we want to prevent from getting in there artificial light obviously but natural sunlight is it's natural and it's healthy that's it should be doing this outside that's why I don't film here too much these artificial lines so tell us about your book um you're writing one more I don't know which one you already have published a couple of books what do you what are you writing tell me about a little bit about your books first second third and what you're writing right now so I've published I don't know two or three books prior both academic medical textbooks and consumer books this latest book is called The Secret of nitric oxide bringing nitric oxide to life the objective is kind of twofold it's partly autobiographical because it it talks about the discoveries we made on how we changed the way we thought about nitric oxide and developing safe and effective nitric oxide product technology and then second it's to build awareness and educate the masses on the importance of nitric oxide because you're a perfect example you're very well informed but yet you didn't know anything about nitric oxide yeah so my objective is to in this book tell the story of nitric oxide and hope people help people to get an understanding of why they need to know about this molecule if their body's producing it and then what they can do to restore the production of nitric oxide because without nitric oxide you get Advanced aging increased risk of heart attack stroke all cause mortality all age-related disease and if we can fix and restore and digest the no production then the scientific and clinical data tell us that we can at least delay or prevent the onset and progression chronic disease yeah so many so many women right now because I receive messages every day you know women asking majority of them struggling with aging and what I noticed right now more women reach out when they're like even in their early 20s yeah it's fascinating how you know sometimes before it used to be like you know when you're 40s 50s you start to have Fine Lines right now I even see sometimes my friends posting something my daughter it was looking lower and she posted her daughter she says 16 I'm like man she looks close to be 30 I'm like wow well we live in a toxic world and the things we're exposed to our daily habits just it seemed like everything we do should stay on nitric oxide production but you can't get blood flow and oxygen nutrients deliveries to cells of the body then they become dysfunctional and it's no different in the skin cells yes and we have to restore blood flow we have to eliminate toxin exposure and then give the body what it needs the body heals itself what will you say right now if someone has a premature aging and watching this video what would you recommend if somebody doesn't know like I didn't know about nitric oxide and you know there is so many things on the market so many skincare products so many vitamin supplements people are just lost and nobody is controlling this kind of part of the of the marketing what would you say top three anti-aging habits or products that woman and a man should start doing it well I think it goes back to what we discussed already stop doing the things that disrupt nitric oxide production I start doing the things that promote it so we already mentioned get off mouthwash get rid of fluoride be on an acids get off antacids and then drink you know we have to drink our bodies you know 70 80 water we have to drink good clean water so hydration is extremely important most Americans are dehydrated at the cellular level so you have to drink good clean mineralized water for hydration obviously taking a nitric oxide supplement one that actually generates nitric oxide and fixes the ability to make it is certainly a good routine and then just eat a balanced diet in moderation you know what you put in your body is basically how your body is going to respond you put junk in you're going to get junk out so I think we have to you know watch what we eat eat good whole nutritious foods and it's a balanced diet in moderation and I think it can be really that simple you made a good point consumers are confused I'm confused I've been doing this for 25 years and there's so many companies out there marketing so-called nitric oxide products that are absolute junk and they're either naive and don't know the science of nitric oxide or worse there's companies out there who are intentionally defrauding and deceiving their customers to try to make a buck so you can't get nitric oxide from chews or gummies or capsules or so-called beets you know there's not much super about some types of beets out there that are advertising yeah so consumer beware follow the science and don't get caught up in this deceptive trade practice and marketing by a lot of companies I have a last question okay if you knew that you will die in one month what will be your regrets in your life that you didn't do something and what will be that you're very proud of like it can be personal life wherever well you know I tried to live without regret you know because every experience whether it's good bad or in different forms us and makes us the person we are today so neither of us would be the person we are today without our life experiences yeah there's some things I'm certainly not proud of the things I could you know if I had to redo it again would I redo it I don't know because it would change who I am today so I don't think I have any regrets you know obviously spending more time with with kids and family you know I travel a lot and it's very taxing and demanding and it's I think a good life is a life of balance we have to balance things and I haven't been very good at balancing my personal and professional life so I would do a better job at that but the one thing I would be most proud of is you know the scientific Community has known the importance of nitric oxide for 30 40 years and the Nobel Prize was awarded for it so we know it's an important fundamental Discovery in science and medicine but the thing I'm most proud of is taking that basic science and trying to to bring it to the masses so we knew that nitric oxide was important but what I've done in terms of developing nitric oxide active products is one of my most proudest moments because you know I get emails texts phone calls every day from people that we've changed their life I mean we've saved people's lives we've changed their lives and for me there's nothing there's no greater honor or reward for doing what you do is hearing from people that you've changed their life I minutes they say if you've changed if you've changed one person's life you've changed the world and you've certainly changed their world so that would be what I'm I'm proudest of you know I'm very passionate about what we're doing I think what we're doing will change the world yeah it'll change the way you know Physicians treat patients for the next several hundred years and I think once people understand the importance of nitric oxide then we give them the information and empower the patient to heal themselves and our objective is if we can make people understand that consumers and patients then they take care of themselves Physicians and drugs don't heal people the body heals people the body the people people heal themselves provided they have the right information education and product technology to do it it's really that simple I love it you guys don't feel it but I just feel his passion you're just so passionate about that look at it look at the smile oh this is so nice nice having you here where people can find you I know you have an awesome Vlog uh where can people find you on social media email I have a YouTube channel where I do put off you know great interviews like this to get the information out there have an educational website at Dr Nathan sbryan.com it's strictly educational I'm not trying to sell you anything but I do a monthly blog get some really cool educational informative videos on there to learn about nitric oxide my books you can find me on PubMed those of you interested in Reading you know scientific peer-reviewed Publications I'm on social media Instagram Dr Nathan s Bryan on Twitter on Dr Nitric uh LinkedIn I'll put all the information in the description box yeah yeah I wanted to say for those who are subscribed to our monthly secret box in one of the months we are going to have a this I have a secret I don't usually tell that but I'm telling right now in advance probably this is a longer secret yeah it's no longer a secret probably we're gonna have that and I believe it it works when I saw him when I came to buy a hacking uh conference I came first day I'm like is that all I'm like what the heck is this because my hacking conference is great for people that don't know like nothing about you know aging and biohacking your body and and uh Health it's great but I I will say I'm not a doctor I don't have your knowledge you're just like a master of that but I do have some knowledge I have read I reverse many ultimate disorders that I had and when I went to his lecture actually I wanted to go there I couldn't and then John tribes would ask Susan and it's just like I'm like I'm not gonna go it's fine just like no no no you gotta go you gotta go I'm like fine and then I'm going with the safe my man I don't want to wait in line I want to be the AP you know I'm like I go there Susan she's like no stay here I'm like see [Laughter] and then I listen to you on my jaw drop about this mouthwash and anti-acids and when you show the pictures of the scarf using this serum before and after I was like man that information is awesome yeah I did my job you did great your job yeah so I was I'm like wow this is amazing I learned something so you were the only one person that I learned something new in this attire by a hacking conference that's good I know yeah people like it's information overload you go to these events yeah and everybody's trying to you know convince you this is the latest greatest life-changing technology and some of it some of it is or maybe but you know there's some of it out there there's there's such quackery that you have to be you know very discriminant on what you do because we can spend our entire fortune in time and resources and energy on doing things that really aren't going to move the needle so what we try to do is look for objective scientifically validated technologies that move the needle on human health and nitric oxide is certainly foundational for everything we're doing in terms of biohacking yeah since I started taking it I noticed my skin looks healthier it's not like that aging backwards immediately but I feel my skin is healthier just plump her I feel my hair getting stronger my nails getting stronger I have way more energy I don't drink coffee anymore and I still have the same energy actually I have better energy yeah I one thing I don't have a headaches I had chronic migraines and anytime I will ask anybody and I even asked Dave when we were in Peru it's like are you taking nitric oxide I'm like what the [ __ ] is nitric oxide everybody's talking about that you know yeah and I don't have headaches and I recommend it to so many followers and friends about that and I I know it works because it helped me you don't want to have headaches because probably migraine is the worst thing that I have ever experienced it's insane pain and it's just like really really suffering so I'm so grateful for that because I don't have migraines anymore no we've we've heard that for many many years and a migraine is a cerebral basis spasm so when you restore the balance of these vasoactive substances which Nitric oxides one then you prevent the vasospasms you prevent the frequency and severity of migraines yeah perfect well thank you so much for being here thank you Gene yeah and I'm gonna leave all the information about him down below in description box thank you so much for watching And subscribe if you haven't bye bye thank you [Music] foreign
2023-08-20