Hack your DNA with CRISPR - VPRO documentary - 2018

Hack your DNA with CRISPR - VPRO documentary - 2018

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Now. That the information. Revolution is, here to stay another, revolution. Is standing, in wait at the door everybody's. Interest in genetic engineering now, CRISPR. Is a technology, that enables, us to totally, rewrite, the genetic, material, of plants, humans, and animals with. All these DNA, technologies. That allowed to do, precise, a gene, surgery, on our D initially, we this. Is a another. Era all, you need to know about, doing your CRISPR, experiment, soon. Sellers. Will be precisely, programmed. Viruses. Can be reprogrammed, they're essentially, software think, of them as apps for your cell phone and, coding, with DNA, will no longer be just for expensive, laboratories, but also for home use come check out where CRISPR, kits are being made. Printing. Medicines, and changing. Your own genetics, will, this soon be possible, my. Particular. Application, is to, write, software that kills cancer cells. We. Get tattoos and stuff like that why can't we. Grow. Tail or grow, wings. It. Blows a lot of responsibilities. On on, the shoulders of everyone and I tell you it gives me goose bumps because I know that, a 20, year old student. At a university, that is learning biotech, today has all the power and technology, at, their fingertips, from, their dorm room as a major pharmaceutical company. That's, a game-changer this. Is back light welcome. To the world of your programmable. Body. Yet. Me to hunt bill 22, comes later, you. A need a photo hard come at, Cana hutong a contigo. Emily Canham. Iconic and also. Co-equal. Video. Hotel clutter warriors, oh and of mer, we have me destined for a chief question homological, no Joe. Just. Easy were, your. Anita, from Hokkaido Hanukkah. And the Okinawans range somewhere. Oh yay, your, parachute, here yeah that's the situation isn't it yes I like it. I shampoo, she, said the kind of bar she's doing tomorrow, he also just need to like wear. Even. Has the genetic muscular. Disease, FSHD. Which, affects his facial shoulder. And arm muscles a disease. For which there is currently no cure. It. Is impressive. Ooh ere the hint who, else to hurt loved theirs, and, who, caught the chromosome, Warka, are, severe, disease they even, have a bitch pair here I. Feel, active and that is hot that is all-pervasive the very Scootaloo, yeah. My. Yeah. I have, made a sidenote billeting. And and come to the hood some bitchin array station o'clock but, her terrible away her doctorate, of medicine. Imagine. If you possess the tools with, which mistakes, in your DNA, could be altered and in, so doing you. Are able to cure almost all genetic, diseases. Imagine. Having a technology, with which you could literally rewrite. The DNA, from each and every organism. This. Might sound like science fiction but, thanks, to this woman, it has now become a reality, she. Is one of the inventors of CRISPR, cast 9 a revolutionary. Copy-and-paste, tool. For DNA, she. Is French geneticist. Emmanuelle. Charpentier if, I have to explain the tool to someone who's not in the science, it's it's, really imagining. A text. With, words and a. Software, a, tool that, allows to, precisely, replace, one. Letter of the word by another letter, delete. A word or a set of words and or replace. Or so the words that have been deleted. By other words so, it's really a, text. Editing. Tool that. Works very precisely, and the. Technology, does exactly this on our DNA and genome. It. Works a little bit like. Programmable. Scissors, that. Can recognize, a certain. Spot. On, on. The genomes of cells and organisms and, modify, the. Genome at at will. Nail. Or - Blanca can all spells of marketing, - Blanca deckle all spelled of main clue came from B'Elanna record all spells that, I talk all saying from the east, dr.. Haley basilar. Precipice, Beauvoir, Thurber clay in getting this formation throat soap. John. Fonda oast is a microbiologist, who, has spent his life researching, bacteria. In around, 2008. He, was working on pieces of DNA in, bacteria. The, so called crispers, his. Work laid the basis, for this new technology, enabling. Us to copy and paste DNA. This. Welcome to seem that it now Alec supplied, towards the a like super, in the 11th, and it's, a stern and revolute. See in the biotechnology disturb, take that that is full. Of new data Lamar fails. Nella and fellow efficient akan and that, is to say that Martin alcohol, still and interlining the biotechnology, mothers out in an ice cream. John. Has been really one. Of the earliest. Pioneer. Willie focusing, on the the. CRISPR mechanism, and trying to understand, really. Those. Molecular. Machineries. CRISPR, are working. For. Me it was important, because he organized, the. First, CRISPR. Meeting. In. Europe that, took place in fall 2010. And this, was for me the opportunity. To, meet for the first time my. Colleagues were working on CRISPR, which. Was very nice because I could present my data and I, called up the first interactions, with with, a scientist. And. They, were all quite.

Amazed, By what I was, talking. About and it was a very, nice feeling, to. Have the. Opportunity. To be congratulated, by. Mike. All the pioneers. Of of. The CRISPR field whom I didn't know so, it was, very rewarding. For, me and also. The fact that I was welcomed. In the in, the community, in a very nice way. Charpentier. Developed. This DNA, copy and paste technology. Along, with American, Jennifer, Doudna. They. Have been lavished, with prizes during recent years. Including. The prestigious Japan, prize and, the American, breakthrough. Prize. Ladies and gentlemen Cameron, Diaz and Dick Costolo. Okay. Just to clear up any lingering. Confusion I. Am. NOT a, scientist. But. I am, a, woman, who has, fallen in love with science and I. Am thrilled to be here tonight, because I do know, that the, life sciences, explored, brilliantly, by many of you in this room offers, us the secrets, to life, the. Breakthrough prize is, awarded to Emanuel. Chopin, TA and Jennifer Doudna it seems only a matter of time before they, received the Nobel Prize it's. Kind of surreal to receive the price from Cameron, and I was just thinking three. Powerful women and I was what I was just wondering, whether you were Charlie. I'm. A geneticist yeah and I always worked on bacteria. Mostly. And when, you work with bacteria. You you. Know that the type of research, that you're doing can. Lead to. Discovering. Mechanism, that could be that. Could have a high potential to develop, new anti-infective. But. I could have also a high potential, into. Developing. Gene. Technologies, because, this is where they come from, from, the mechanisms, of data analysis. Just. Like humans. Bacteria. Are also bothered. By viruses. These. Viruses, release, DNA. In bacteria, telling, them to make more viruses. But. Bacteria. Have their own defense system, against viruses, it's, called CRISPR cos it. Can recognize the, DNA, of viruses, enabling. It to precisely, dissect. And destroy, it, sharp. Aunty A's team investigated. This system, and along, with Doudna they were able to create the DNA, copy and paste system, that is now known as CRISPR, cos 9. Allowing. The precise, and accurate, reprogramming. Of DNA, not, only in bacteria, but in any desired, cell. It's. A technology that, originates. From. Evolution. In bacteria, and, what I like is that it allows, to study the, evolution of, the, world the, interesting thing is in fact we use. Evolution. To change evolution, somehow exactly, we, exploit. Evolution. To. To. Impact. Evolution. And act under on the evolution. To. Passing a fun at CRISPR system design, hell-blade bikini.

Mechanics, Genome editing and, that can be taken the, heat phenom from the bacterial leaf element of allah chris'll that i never track of of biotechnology. This home um. Microorganism. The, Hebraic on the powder into some product, the, market, and, it's a sternal a velouté in the biotechnology, disturb, take that asked full of new data llama fail. Sneller and fairly efficient akan and that, is to say that martin health also still and interlining, the biotechnology, mothers oakland there's a nice screen. Even's. Muscular. Disease is the result of an abnormality, in the DNA, located, at the end of chromosome, fall as, a result, a highly, toxic substance is, generated, in his muscles, which, slowly breaks down his arm shoulder, and facial, muscles. Unfortunately. There is no medicine available but. With CRISPR, this, genetic, disease may possibly, be repaired. Yeah. The clinks, horn iconic, killer. Science. Fictional, my. Al cetera couldn't be done. Erica. Mena Kyra, honey connects design from Daisy sector, that is, fell. Below friend and. Hail. Interesante, little look. Yeah, the age of science. The. Era to compete jihad jihad dude I know. I look. Man I need, result. Of chromosome. Clipper yeah, give, it we seek to understand. Though. The quad chromosome yeah. At, Clarion thrusters. Him. Is genetic, researcher. Niels kaizen, Deanna. And even visit the who pressed laboratory. In Utrecht, the Netherlands, where, Hazen, is attempting, to find a solution for Ivan's muscle disease by using CRISPR caster change his DNA. They. This. Is a multi-layered. A lot who's here vacuum meth molecule and act like admist belong like molecule over maybe he react is, Dana. This. Here. Convert. Yeah Hainan, society. Stock you stayin are the the the Cody era for home about David's. Convey. In yeah, for but idle at. Ur in seller into, bow so. That's adults can converse. To do and, eighth. On the Hanoverian, archaic is the Dukes, fearful, but obey out some, problem saved you next, and. That's had, a that certain Yahoo speedy the staff of him and there was a crowd which, done and guess who does a tan stats over the. SPD other states smoker, mmm. We. Do most best lead, scene so. Yeah, it's like a commercial. What. Time problem is actually case doctors enzymes, beer cellar button a Metallica. Max of ash look nice remarks of mood of order and not a bit easier freezer this.

Longtime, Staffers. And spear seller insert, resists, and Hall sensors routers and Muslim. Latter on the telephones and Liam of Midori. State soccer would and before. Token first article, at site work against with a stone, emojis. The toner this icon new hood nears Linda her. My. Doctor. Thomas inácio. Go bubble, teas in the death machine hello hold it in that's, ice leds and dosa off seller, the other days, simplest. Problem. It's a crisper, costs errors, in it DNR, and connect to Makkah Bardo. Dr. Shulman problema, safe to some crystal Davis actually. Out was Edward. Met. Chris Bukowski nerdy, nerdy vampire. Who laid on Moloch after, Omaha. For built the numeral cellar, in at laboratory, amenities, and the bustle so that's a pal the foul to give up fold in a day and night even in a passion to Celestine that we could map out in at love, so. It's vampires. Later on project about and bomb of endless var, over date and that. This new in each, part into a case of murder for McCarrick on Sanders at, a stain a norm for Snelling, opal a fretful not on the hook and that or, could fill me a today to come in feel Cortana, type this, dot objects, Elif is all revolution. Air and. What hasn't been taken and almost not so Chanel now. Magazine, is Dartmouth, either a new eternal he worked on tickled and disco, fellowship kiss / cosmonaut hi talk over a, gnome, sequences, the day now for the canova Paulo of halo. On the return of he ever mayonnaise, ding akan seen deer for hey noise cones in the haystack. And enormous for Snelling from Kenneth and. And and I adore Oakley Rufus nailing from the to Priscilla at Anglican, a schooner. Mar. It. Had no states and long at idea for dots percent, error I time the. The, first of our hamburger not. Keg. Not for owns in, at laboratory, success. But a cantata starter history. It's neat corner and from there well, my. Dion. Decking are based on to yoga, and the, federal adult wiggling from some techno he totin Totenberg like to pass by a therapy, that's it so no 1510. Area Titian in. My opinion the problem that we have developing, medicines today is that it takes too long and it's too expensive and, so, because. There's such a large investment of time and money to make any drug product you can really go after only, the largest diseases, and largest disease groups. Crisper, cast nine is just, one of the many developments. Which are greatly expediting. Biometric, research. Andrew. Hessel is a synthetic. Biologist who. Has worked in the pharmaceutical, industry for a number of years but. His greatest, frustration. Is, the pace at which new, medicines, are able to enter the market so. He decided, to go his own way I, wanted. To hack the biopharma, industry, and and. After, I left the pharmaceutical. World I thought well what can a single, individual, do to, really change the biopharma. Industry, I was unattached, I wasn't, with a university. Organization, I didn't, have a company, at the time so. I had to think of some idea that would that, would ultimately be, big enough to change the world I called it not big pharma but big idea Pharma. One. Of the places Hessel worked for a while was at the software company, Autodesk, this, firm produces, 3d, design software. While. There hessel, was occupied with the digital, design of biological. Systems the. World, of computers in biotech are really closely related in terms of just, architecture. The, cellular, architecture, in the architecture, of our bodies actually is very close to the architectures, we've created in, computers, you, can look at the cell as a computing. Device and a manufacturing, device it's like a smart, 3d printer and the. DNA, of that cell which, manufactures. That cell and runs the operations, and, it actually dictates, the construction. Of the housings of different components so it's like a really, smart really powerful really, programmable. 3d, printer. Once. You understand, the architectures. And start, to digitize, the processes, you realize you can go and make a digital biology. That's quite accessible, and very. Very powerful in terms of manufacturing. Slowly. We, are beginning to control, DNA. The genetic code, of life, DNA. Is comprised of four substances. Designated. By the letters a C, T, and G, the. Sequence, of these substances, determines. The genetic, code of a cell with. CRISPR, we can now accurately read, and write with these four substances. And thus, reprogram. The cell but. This is still not enough according, to Hessel in terms of programming, we're still down working with the bits in in, biology it's, a's t's G's, and C's in, computing, it's ones and zeros we're working at the bit level most of the time to assemble the code that, is extremely, hard but what we've been seeing over the last 10, or 15 years as synthetic, biology, the field has come into play is we've started to modularize.

Those. The, instructions, we're saying this little bit of a STIs G's and C's is a switch, to turn a gene on so, now we just call it a switch you, know and and, then we build another, system. That is Oh a reporter. Oh and here so we start, to functionalize, these code blocks and now those code blocks have, the code the genetic code, encapsulating. Them you never have to look at them and once you've done that now, you can start to assemble those code blocks and say here's, a switch here, is a sensor here's a reporting, device and you just drag and drop the components, to build a new circuit so, now it becomes accessible. To, someone who isn't a biologist, now it can now, someone that is familiar with even wiring, a simple electrical, circuit can now build a simple biological circuit. And that's why we're starting to see kids literally. Seven eight years old starting to build their first biological constructs. Josiah's. Aina may no longer be a kid though, he may sometimes behave, like one. But. He is a real biohacker. He. Sells crisp packets on the internet to anyone who wants one. He. Once worked for NASA but, found it too bureaucratic. His. Living room has now been transformed, into, a packing, division for biomedical items, hey. Everybody we're here at the Odin in West Oakland California, come, check out where crisper, kits are being made. Over. Here. Starting. And left, back, we have Allen and making. The media. Micah. Peter. And. This. Is the. Kids we make and we ship out the people so our. Kits come with everything. People. Need to. Do. CRISPR, experiments. You. Don't need anything no. Experience, at all. So. I grew up. In. Like. The. Late 90s, when. There's like this whole, computer, hacker type of culture right where it was like you. Learn. How to do some cool stuff and then manipulate, technology to, get it to do what you want to do, well. I saw that like biology, is this interesting, technology. And, maybe. Different aspects, of biology can, be kind of hacked, this. Idea of like a biohacker. As opposed. To say a computer, hacker, started. To be born in my mind and. I. Started. To try to develop ideas, and. Experiments. Along this line and I, thought well maybe I could make a kit, and, get that in the hands of people to show them how to use this technology, and. Then people you. Know got really excited, by CRISPR, I think the. Coolest thing about CRISPR, is not. Necessarily, like. All. The genes that can edit and all the things like this it's not like, everybody's. Interested, in genetic engineering no say. Even people who are like anti GMO or. Like didn't. Like GMOs now, those people are interested, in genetic engineering because of CRISPR. Zana. Experimented. With CRISPR, on himself, he. Attempted, to make his muscles, grow more quickly the. Attempt, failed but, his enthusiasm only. Grew. My. Dream is that it, becomes. Like. More, open, people become more opened human, beings changing, their own genetics, as. Adults. Or as children, um change. The way we think about being human, instead. Of just everybody. Being born with the genetics, they have for the whole life. Maybe. We can start changing that up and and for. Interesting. And fun stuff you know everything, doesn't have to be, everybody. You know cure. This disease cure, that disease you know it's like you know we, get tattoos and stuff like that why can't we. Grow. Tail or grow, wings or you, know you know how much scientific research has gone into like growing a tail and human beings probably like this is none but, like a lot of people probably think that's pretty cool. Companies. Can do that if this technology opens up like growing, wings who knows that's even possible probably, not but it nobody's. Trying alright. Like. Different things you know changing. Your hair color or, skin color growing, more hair or less hair. You. Know there's there's, so many opportunities. For. This technology to be more than just. You. Know another. Medical, treatment or another. You. Know, technology. That only big, pharmaceutical. Companies, own we. Think that genetic, engineering is such a powerful technology that. It should be accessible to everybody. So. In effect, nobody. Owns CRISPR and everybody does right it's. Kind of like. You. Know any any, sort of knowledge like it's like saying who owns now. I mean. Some of the academic publishers might say they do and. Charge you $100. To read a scientific paper, right. But. In, fact you, know knowledge isn't. Owned. Zana. And hassle, both, have the same goal, making.

Biotechnology. Accessible. To everyone, Zana. Does this with his CRISPR kids and, Andrew. Hessel through, making biology, digital, my. Whole goal, was to bring, the tools of biology, into, the digital world digitized, them as much as possible make them automate, and make them accessible via computing, and put, a an open-source, business foundation around it so that we can share information and ultimately. Build. A community, that, can work alike. The pharma companies. With. Digitizing. Biology, hessel, means creating, on the computer, viruses. Containing, DNA which. Could then be utilized for instance, to help fight cancer. Viruses. Are really, interesting, biological. Agents, I do not consider them to be alive I consider them to be software, and you, can if you buy a software, program, it is not alive unless you load it on it does not operate unless you load it onto a computer so, a virus by itself, is a bit of protein and a bit of nucleic acid, either RNA, or DNA that. You, can think of as, a. As almost like a floppy disk if you're my, age or a, memory stick today if you're if you're modern, it is a program, loaded, into a physical, structure that. That physical. Structure will dock with a cell and load, the program into the cell and now most of the time the program is make more viruses but. We've gotten, very good at engineering viruses. To deliver, programs that, we think are interesting into the cell either make, this protein it because it's a good drug or or. We, can load a program into a cancer cell that says die so. Viruses. Can be reprogrammed, they're, essentially, software think, of them as apps for, your cell, phone. But. We. Have this opportunity enough to start to design viruses. From scratch it, is, a way of making. Programs. For, biology, that can then do useful things so, the virus is simply the way to load, software into cells and add new applications my. Particular. Application, is to, write, software that kills cancer cells. All. Tumors, are different and with, his new company humane. Genomics, hessel, wants to create cancer, fighting viruses.

In Which the DNA is precisely, directed, at the tumor it must fight. Special. DNA printers. Will be able to print the specific, DNA, and place, it in viruses. In this. Way everyone, will have access to personalized. Cancer, medication. And, now. We've partnered with a group in Alabama, at Auburn University that. Has a veterinary, school and research center to make. Cancer, fighting viruses, for dogs they. Had done some pioneering, work with genetically, engineered, viruses, oncolytic, viruses, for dogs I've. Met a doctor there by the name of dr. Bruce Smith and said. Let's upgrade your technology, let's. Go into the world of digital design, of viruses, and so, last year in 2016, we made the world's first synthetic, cancer, fighting buyers for, dogs you know we've only built one synthetic. Cancer fighting virus this year humane, genomics, will make about 10 viruses, and treat, ten dogs. We, already get personalized, trainers, personalized, diet you, know you. Can get personalized, clothing I believe. More and more of our medicines, and medicines. That keep us healthy and think of them as vitamins, should. Be personalized, as well and, eventually. I can see having an EpiPen type, device, that. Has all essentially, a pharmaceutical, company inside. The device, and, you know the doctor can upload your medicine into that device and. It just goes beep when it's ready and you do an auto, inject. So. That's the future how long it takes to get there. You. Know really depends, on our will, but, but there there there. Is nothing science, fiction in that process today we're, already seeing the miniaturization. Of all this equipment the, design tools are already exist in the cloud and ultimately. Single. You know single-use, injectables, are used. All the time with things like EpiPens. Hassle. Suggests, that for around a hundred dollars you'll. Be able to get a kind of medical netflix, subscription, to keep your DNA, healthy, these. Are now only ideas, and tehsils company is just getting started, but, fiddling, with our DNA, is already becoming commonplace. Reading. Your own DNA, DNA. Analysis, designing. And printing DNA. Codes copy, and pasting, DNA, using, CRISPR, it's. All becoming, cheaper more accurate, and easier, as easy as child's, play we. Got the, bacteria. And these little little. Vials. They're. Hard to see because they're bacteria you know. These. Are special strains of just lab ecoli. Non. Are harmful, non hazardous. Non-pathogenic. They can't cause disease, or anything and the DNA where does, it come from we, actually get, it get, it synthesized, from companies. And. Then, put it in these little little, tubes. So. You can see it frozen in there, frozen. DNA. So. A, lot. Of these things are very science, specific, and really. Expensive if you actually bought them you. Know from. Companies. So. We got this. Holds tubes, we. Got pipettes, some. Pipettes are, basically, devices. That allow you to move around small amounts of liquid. They. Suck up and move around liquid. Every. Scientist, needs one, we, got tips for that. You. Need chemicals to help get the DNA inside, the organism, and. Then we need the. DNA put. These in the kit the. Guide. All. You need to know about, doing your CRISPR experiment. And. Where is it going this. One is going to the bag in the Netherlands. Experimenting. With DNA, in a back room or, garage it's. Reminiscent, of developments, in the 80s when Bill Gates and Steve Jobs were, playing around with computers. But. Playing with DNA, is different from playing with computers, the. CRISPR, technology has. Traveled widely during, recent years. Experiments. With gene alteration. Are now going on on a global scale and. Experiments. With the genes of embryos. A. Number. Of countries, have already, started, to. Apply the technology for, research, purposes, on human. Embryonic. Cells. So, at very, early stage. So. Willy a few, a few, number of cells, to. Allow to understand. The only, mechanisms. Of life, that. Can be also interesting, to understand because there are certain diseases that develop very early on now. The idea, to use a technology for, human embryos, or human germ lines, for. The purpose of modifying, the. Genome for after. Reimplantation. In, the in the. The. Human bodies is it's another, story Sony for, sure here's our strong, ethical.

Issues. Because. That's one of the concerns of God this is one of the of the of the concern is that the technology, would. Be young will, be used beyond. Its its initial, purpose. That. Is to treat, human. Patients, but. It loads a lot of responsibility. On your scholars, it. Loads, a lot of responsibilities. On on, the shoulders of everyone, our cervicals and. Specifically. Scientists. Developers. And, clinicians, have a, role. In in, in. Making sure that, the. Right regulations, are in place and. That the technology is correctly, used. For. The the, purpose at least for medicine, which is to to cure patients. In, the, Far in, Amsterdam, the, boundaries, of art science and technology are, being explored. It's. Also where a biohack. Academy, a do-it-yourself. Lab for biotechnology. Is being organized. Anyone. Who so desires can be inducted, into the world of biomaterials. And the cultivation of, microorganisms. Oh. That's. It the. CRISPR. Clip. On. The, basic CRISPR, course they're, learning how to play, with DNA, all. Right so, there's tubes. It's. Glass. And. Then, here's the. Thing. That actually is. The most important, the little tubes. They're. Also really cool so. Here's the RNA. We're going to add in the transformation. Buffer and the. Plasmids. So. It's, how much it is. It, sounds, fantastic we, can all now play with our genes using, the CRISPR technology, but. If we really want to create medicine. The, business, aspect, of it will soon be peeking around the corner, there. Is a real patent, war taking place for the rights to the various aspects, of the CRISPR technology. In. Boston, this all comes, together. Boston, is a club complected, even an old sport -, yep MIT, yep, Harford, and, on all the instituted. Domains, of the Broad Institute does. Health or health the see, the high scream enter, the, study at no chiffon the solemn. John. Thunder oast has, the patent, on a component, which can be used with crisper, and he travels as an adviser to various, businesses in, Boston, also, possessing, component, patents. Even, in Boston on an. Anthelmintic week, we also noticed or phone saying, from. MIT. Brought and/or Keith. Young from, Harvard Medical School, um, da in front. Our list, at the cameroon, pharaonic. Hexamethylene. Lungs by by editors the, america for clunkers in, the mark. Felt, blog from from kasnia tomahawk, from from. Coast for a life of shape EF rain and. For foreign foreign. To passing in, Hama Hama part. Of yeah. The fourth unfunded Natomas, uber owns, for, trunk from Shannon, a home cook anyway. No cabinet, of of, the via Molokai design. The Bondurant island, for, the summit of elegant. But. No one is willing to reveal all. Even. Fonder oast doesn't, always know what the companies, are working on. Design. A medicine, called an top driver, boom. The CRISPR technology Dubrovka. Romantic. This anti, Parker and it. Needs, validly, be drive from a basic design and that Vitello, submit all tied Mike. Forwards the, drive here in Boston editors. She. Dad of the website guides the Cedars and ferbots, secrets, dr. o of. Blue top conquer, and of, the Laver. Structures. And then, the other class. To existence. At. The end then you can you, get unwinding, of this part and then swinging, in the. The. Dual Aquila style payment okay. Shelton. Freedom edit edit, that so eloquent dr villa see, holodeck mother held up and on it. All Duncan is a new African. Team from Albania, whole not Mencia observed. Been clocked and at, Cana - kolima I met him it made, excellent health every. Day you will help I. Need. A you for health yell oscilloscope, internet that. Severe, and successful, at. Heart in the habit of homeless. From home on million dollar listings. In like. The. New companies, editors. Caribou. And CRISPR therapeutics. Are all owned by people who were present during the development, of CRISPR, it's. Estimated that with CRISPR, over three thousand, genetic, diseases could be cured if. This, can be realized, it would result in a tremendously. Large market, each. Of these new companies would, have the potential of becoming the new Google, now. Becomes is called the TB Drive in. That, in. Iran film, taken and it will occur but, what about Apple and Google why any Bo informatica, of informatica. From. Cannabis Clara that's, I knew the. Drivers editors in Caribou, Madison, developer the. Designer. A norm, and we have similar. Coke. In debility. I hail, help. Along like Varrick from aquatic life and and desire like daily, technology. Not, a marked the, program is. It or not fire that's to Phil Marquez or sapling Google.

Yeah, That's. Sarek. Needs, a, machine that, is a hood on my omelet, half cut in half tower by, the movement rifle craving, of Quebec and horrible and eat commences. The. Biohackers. In the VAR still. Have greater concerns, than just the patents, it, may. Now be easy to play with jeans but if you're really going to alter, your jeans there will be problems, to confront. Ok, so now we're at the last step of the protocol. First. We'll discuss some where their societal. Issues around CRISPR and then we come to the last part which. Is, are. We going to do it are we going to heat shock their. Cells. Or, not. The. Bio hackers, are nearly ready, the. Original, idea, was to use CRISPR, to make bacteria, resistant. To an antibiotic. The. Latest step, is to use CRISPR, to give the protein, in bacteria a, heat shock as only, then will the genes of the bacteria, be altered, but. In the Netherlands, you can't just alter, the genetics, of an organism. But. For this CRISPR. Kids we actually don't have the license, so, when we do the heat but that would be illegal. From. That perspective is. Punishable. By by. Once I. Think. I think. This is a bit of a gray area I don't know it's. Also something that's not been, tested. A lot I guess at least I haven't heard of it because. Of course it might be that people do this in their garages. Or kitchens, and have, used this kid also in Holland because we could order it with. Not, a lot of trouble I mean, do. I on the, border. Control didn't. Pick. It out. But. Then the, whole thing about rock societies we try to make it transparent so. I. Mean. It's even videotaped. So. This. Means it's it's a different situation. So, that's, good of course because, this. Maybe make it debatable, I. Don't. Know how I mean, it's illegal it's on obscenity legal. If something happens you don't know what will happen because we, don't we are not trained as a you are of course training we are not trained as biochemists, so, we don't know what we should do then, I'm. Not sure if we can do it with that's amount of knowledge, yeah. But. The actual because it goes further than just editing, it be resistant, to the into. Antibiotics. So you can go from way further and, I think that that this could be the beginning of well, it is already the beginning of editing, something that's a much. Larger. Picture. And that's the question not, not. Only if to make this part now what we're doing it back. So. The question is are, we going to do it or not. With. All these DNA, technologies. That allow to read the, DNA that allowed to do, precise, gene, surgery, on our DNA surely this is another era but. You can't control let's, say the effect, of this, technology globally. Know. The. The the critical aspect of any. Technology, that is developing, such, as Chris Parker's 9 is that. First. Of all different, countries have different regulations, in, terms of of. Biological. Ethics, and this. Is a case for Chris Pakistan, so different countries, have different views, with, regard to how far one can go, to, apply Chris Pakistan, for example in in humans and it. Would be difficult to get to a, general. Consensus. Because. Of different types of cultures and different. Ways. Regulations. Are already, in place and, difficult, different, let's, say ethical. Idea. Yeah, in. Different cultures indeed, indeed, so, the different, cultures the different ethical. Regulations already, in place surely. We. Will bring that it will be extremely difficult to, have a consensus. On, certain. Applications. Globally. Alright. I think we should have a fold. So. The heat bath is here it's at 60 degrees. The. Next step in the protocol is heat. Shock. Who. Would do it I mean I want to see hands. Then. We won't. You. Have to understand, though like, people. Are scared of a lot of Technology these days artificial. Intelligence right. It's, gonna destroy the world. You. Know genetic, engineering and CRISPR, it's gonna destroy the world honestly, if, like the printing press was invented today, they probably wouldn't let anybody use because. It would destroy the world right, and if you go back in time and say what. Has caused the most damage out of any technology you might say it's the written word right like wow you know look how much damage has been caused but look how much beauty has come, because of it same thing was like cars and automobiles right. Every. Year, millions. Of people die and you. Know automobile, accidents, and. We're all ok with it because it. Brings us so. Much in, our lives being able to travel long distances, in, very, short periods of time and. I think it's the same way with. These, genetic, engineering technologies, like CRISPR. Obviously. Everything. Can be used for bad ok, everything. And bad, stuff can happen from, but. What what's the possible, benefit, of this right what's the possible benefit, and the benefits, are you, know really immense, we've. We've done the groundwork with, biology, and digitizing, it then you, can go to digital libraries, of information, there's gene banks, of information, there are now databases.

Of Synthetic, biology tools and processes there is a digital architecture. Where I can now get, online. Researchers. And tools and equipment and services, and soon. We're. So we're just starting to get the acceleration. Now we're just getting hitting, the knee of the curve where, this is becoming where there's a large enough community, the tools are cheap enough and accessible, enough and connected. Enough to really start to accelerate and I tell you it gives me goosebumps because, I know that, a 20. Year old student. At. A university. That is learning biotech, today has, all the power and technology, at, their fingertips, from, their dorm room as a major pharmaceutical company. With, just a little bit of funding and that. Is that's, a game-changer so we, are going to see an incredible acceleration. Over the next generation. We'll be surprising. To many people, Madame. Vanir. Vanir. They're. A total shock so moolah Carnot a net force pillow from who long Catherine, take the. Same the powder on decking epidemic, we have AB a, Mensa. Dr. Fernau this had no yeah, and. A Nolan a skullet on. The other accounts, like, a sumo processor, Oaks often horror stop. And loss diameter and then looked, at my knee tonight, this. Is false Hillier who looked at for spelling no, lateral hope yeah that's it. Oh. Yeah. Nope it's Rita. You're. Done otherwise, there. Where's. The first one thank. You for watching, for. More on this subject take a look at the playlist you. Can also watch this recommended, video don't. Forget to subscribe to our channel and we'll keep you updated on, our documentaries.

2018-09-22 01:55

Show Video


sticky shit, only imagine how powerful can be human made viruses !! I hope they work on anti viruses too !!

My DNA is God !

English subtitles please.

No problem, it happens to everyone. Hope you enjoy this documentary.

Oh. I forgot to activate the CC. It's my bad. Sry.

The subtitles are in the Closed Captions.


This is an extremely well done documentary, maybe life changing for some of us. Greetings from México:)

And greetings from The Netherlands!

Thank you so much Roberto Milán. If you would like to, you can share this documentary with your friends, it will be very helpful to our channel.

apps = apps for your cellphone virus = apps for your cell-foam

Well played.

This sort of technology should only be used to advance humanity, but with our society as it currently stands, I can only see it being used to compel more competition for monetary gain. It is nice to know that such potential is available to us one day though, I hope it becomes viable fast enough for Ivan, and people like him to be cured.

+vpro documentary Yes. Over 50 % of revenue on the internet was pornograpgic in nature for over a decade. We'll see.

+Tim Kuhner

"Pornography second"...

Just look at the internet, and you will see the blueprint that genetic technology will be built upon. First and foremost advanced scientific and military efforts of course, but pornography second. Then all the other uses came into being. I wonder how that will play out.

These animals continue to destroy humans using technology.  How about solving and finding cure for cancer which is a man made disease?  No they cannot.  They are talking about rewriting DNA of humans.

Well. If scientists hadn't questionned "what if"... then you wouldn't have medication, vaccines, cures for diseases. You mean you do not use any of the modern science or technology?

vpro document:  Let us see you cure cancer and many of the diseases that scientist  keep breading and introducing in to the human population.  I don't deal with what ifs.

Well, what if you can reprogram your body to fight cancer?

N. A. 1234

Exelente documental apoyo a la revolucion genetica esto ayudaria a millones de personas


Somebody stop Josiah Zayner before he screws this world!!!!!

What do you think would be the worst case scenario?

I don't understand what that cell biologist is speaking. You must have subtitles orelse there's no way people like me would be understanding it.

There are subtitles...in the Closed Caption. Enjoy ;)

I don't even understand what that kid speaks. Subtitles please

Subtitles are in the Closed Captions.

Women empowerment in science!

The techno-progressivists and the like are running rampant. Tempering with DNA is not the same as tattoos, and making this technology publicly available is a disastrous idea...

Using evolution to change evolution....

Men/women with tails will be the new transsexuals...

Very interesting and well made documentary!

Thank you Guustaaf! Maybe you can share it with your friends, that would help our channel. :)

Imagine some edgy kid in his basement trying to create a zombie super virus

....or a mad scientist somewhere in a government lab? ;)

This is beautiful dreams

Please provide English subtitles

Thank you Manoel!

The English subtitles only apply to the non-English interviews in the documentary.

It already have subtitles in english, french and spanish. Just enable it on youtube.

Yee hah

Poderia Legendar o documentário em português BR ? Não consegui entender muito espanhol.

I find this a very thought-provoking documentary. It gives the impression that this technology can be used in both good and bad/evil ways. I hope that humanity will be able to use it in the appropriate way.

Absolutely astonishing !!! :-)

Nossas desculpas, nós não legendamos os documentários em português no momento.

why the fuck not everybody speak english, are they retarded ??!!

The elites have probably been changing our DNA (somehow) to their advantages for years already?

Muy interesante, pero podrían mencionar al menos a Francis Mójica

A lot of potential both good and bad. But for the good this will do, she's simply got to get the Nobel at some point. Him too.

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I'm beyond that. Male or female she's just a great scientist and worthy of at least a Nobel.(Egalitarianism trumps both feminism and actual misogyny).

Grow tails and wings? Um, cuz we don't n eed them!

Imagine this technology coupled with nanotechnology coupled with chemtrail spraying. If that doesn't blow your mind, then you have no idea what any of these things are.

WTH are they thinking? Don't they know this is exactly the reason for the flood that wiped out Humanity (all but a few) back in the days of Noah? Are they just asking for Humanity to be erased?

Definition of evolution... Dude!

James Flames yeah, I think crispr can do amazing things for mankind but I worry about a hitler 2.0 in the future using this for death and terror.

Grow tails? There's a rare cellular nucleus mutation that does that. Google search images of people with tails. Grow wings um... okay that's cross breeding mad scientist territory. How about Platypus beaks? of Tyranosaur heads? or whale penises?

CRISPR cannot be used to unmutate mitochondrial DNA mutations. They would have to get past the outer membrane of the mutant mitochondria. Mitochondria are protobacteria. Plus CRISPR would have to be able identify mutant mitochondria and diffentiate them from normal healthy mitochondria.

YouTube has an automatic Closed Captioning. tap on the screen and tap on the 3 dots on the upper right. it's not perfect. CRISPR becomes 'Crystal. '

+P C BARR gods a lie kiddo toughen up

+P C BARR lmfao noah

talk2me9ja cancer is not a man made disease you idiot.

..or a mad scientist somewhere in a medieval castle trying to turn the whole mankind into Aryans by spreading an unstoppable artificial engineered virus. That rocks ! At 1:12, the scientist suggest "Why not grow a tail... wings...". Great ! I need both ! And purple fur ! And glowing eyes ! Is the ability to cast spells from the demonic plane a genetic ability too ? If so, I need that too ! NOW !

*Real question: where are the “black” people in that award show? Do black people not exist in France? Are there no black scientists in France? Cameron Diaz isn’t even French or a scientist! Who flew her out there?! Why couldn’t they have Condoleezza Rice giving out that award... or Tina Turner? The future is grim for “blacks”. It’s ridiculous how these scientific discoveries come around and we still can’t even find a cure for such a primitive illness: **_racism._** Please cure the human race of racism already!!!*

D S *Thank youuuuuu*

James Flames *We have the 2nd Amendment in America for these potential scenarios.*

The guy who sells the kits sounds like smarter Bart Simpson.

I am an Indian Muslim. I am an environmentalist and depopulationist (work for global birth control)! If gene editing can done successfully, it will help millions of poor people! But religions are barricades! They say, diseases from god! Religious people can clarify about this invention!

In the present world, human races have so many deficiencies! Using gene editing technology, new generation can escape from incurable diseases. for that we need birth control! (pls. visit www.questmenism.com)!

real life furry's? O.o

yes please

Would you give permission to use some scenes?

Imagine CRISPR/Cas9 + advanced artificial intelligence. 40:49 and as usual governments would set some kind of prohibition on this tech just for personal gain.

Plants, humans & animals...hmmm


Hiv viruses when is the negative?

No. Diseases dont come from god.

Where do u think white ppl come from

So furries, customizable pokemon and super humans will happen at the same time in the future. ... Now is when everything goes to shit, right?

I'm surprised some stupid religious nut is not complaining because they would rather we remain stupid and a slave then smart and free

Grow new hair for baldness kit ~~~~~~find the gene for baldness ?? and i will patent it

Mel Vern has nothing to do with need. We do not need a lot of stuff that we are blessed with today, but it is stuff we like or want.

after copy and paste comes auto correct.. and we all know how entertaining that can be now with text editing.. just imagine...

you sound like a religious moron trying to stop the advance of knowledge.


I think if you want humanity to be safe from this technology give it to every one not just the power hungry politicians or the rich and corrupted

WTF how bizarre life on earth already has and is cross breeding on a variety of different levels.

james Flames:Its going to happen,They doing everyting that it wil,very soon.

wow . this is freaking Amazing. I hope we don't screw something up.

The documentary was great. You know what was even greater? The comments haven't been flooded by biblethumpers trying to cram their religion down our throats. I can actually go to the comments and engage intelligent conversation this time and not have to swat mosquitos while doing so

Thanks Llewellyn Thefelon! That is what we need, interesting discussions!

This is maddnessssssssssssssssssssss,oh God protect usssss!. We are Doomd,it the and of the Humanity,life as we know!. We moeten deze contennen,barikaderen,aan vechten!.

Robert Milan: We are here in West Europe!.

I need you all o understand something...from this video you need to know they can cure AIDS and they choos not to

the experiment they were pondering with the mail order crisper kit was to make a bacteria anti-bacteria resistant. that sounds weaponized. no wonder countries have laws against doing this stuff. whoa.

I have my DNA hacked only the old fashion way. Ideally in the horizontal. With the help of fitting XX chromosome carriers.

If it is left to come down to what money can buy ..... Bronyism movements will flourish. Capitalism the neo-religion, tweak your imperfections... Feck working on any integral constitution. Gattaca 1997

And like 44:00 That guy saying how the written word was. Wow Changing genes curing things through stem cells and D.N.A. The guy is on the level. Makes me wonder about the idea of how easy that really is. If it just comes down to some simple breakthrough to stop the aging process. Because the implementation is easy enough. That it can just be givin out like the small pox vaccine only to stop aging. Just takes one breakthrough. When it approaches that there will be a breakthrough to everyone. I was not the Jonny newmonic I am left in the dust not a slave. I had certain things in my life. And what becomes of one that does not age for a very long time. The ancients used tools to prevent brain swelling how did they choose and at what time to implement them. The breakthrough is probably as old and as generic as the D.N.A. CODE itself. And what would people in the community say to a person that is living for 150 plus years without real signs of aging. Does it become a world wide opinion sequestered for that person as to the meaning of life no joke why they are there with no one on earth laughing anymore to convince that one person that we were all here for them for the sake of good on the deepest level the whole time and that evil happened sometime after that bare bones base quality that every human has but is ashamed to admit. Is it to prove to the dumbest for physical reasons once again the world can be sequestered to help them everyone at the same time to prove to them they are indeed the smartest person on most levels when everyone is there to help. Everyone helping the one person out seems to be the common factor here on this earth does it matter if you live at all or not. In this world. The POINT rally up on. The method for the underdog. how many times before all of our dreams come true to the point that hearts explode.

so it is like HTML, including photoshop on steroids for human beings but on a DNA level

We should only use this to make our immune system immune to all diseases on earth.

I really don't understand people. GMO is bad as hell, but finding a cure for a cancer and other diseases compared with f * cked DNA is desirable. No matter if the method is based on the same technique generally... Ridiculous :) I hope that the future will come sooner than later. Greetings from Poland

This is very misleading. It's not that simple and ready for everyday use for muggels..

+gaijin geisha

Life and consciousness functions as a quantum computing system. Our body damage 50-70 billion cells daily, which are repaired/regenerated at lightning speed and at 99.99 % efficiency. Without knowing about this quantum computing system, genetic manipulation will never succeed.

Just another way to rip people off. Why are these people talking about how great it is and the one guy couldn't even manipulate his muscles? They are just advertising a product they personally are able to make money from. I don't see how you can compare a printing press or a car to DNA . So a few people die so what!! Excuse me!!?

Messing with your DNA is dangerous and why would you want a tail??? Sound like these kits could destroy your life. Nothing to play with..those guys scare me playing with DNA and mailing DNA to others that have no education in science is just plain irresponsible..and dangerous

Hate to think of the cost. Insurance companies and Pharmaceuticals $$$$ who will be able to afford it?? Only the very rich

Had trouble even with the subtitles

Ok, so then AI is created that can manipulate DNA, and then they take over the world.

Fine honey throws cup in trash, take DNA, copy, paste...... BAM!

Being able to copy your DNA when you are young, and then as you age just copy and paste your replacements into place..... live to 500 yrs old.

The future of slavery.

All we need now are more affordable robotic legs made out of aluminum ;)

Oh ok, so THIS is where are the monsters are going to come from. I get it now.

Standard fear response.

Nope its going to be free. Those big giant companies... they're all going away. They just don't know it yet. This is already quite inexpensive compared to older medical technologies.

Very nice documentary.

Must watch everyone.

oh they forgot to mention on key bit of information, after dna is changed, it can not go back to normal, only further abominated and passed to further generations of glow fish.

Josiah Zayner is so disgusting, he is truly sick, obliviously he is a protected tool

+jigga jaw Standard dumbass response.

Y, because its not what it was meant to be.

+jigga jaw Yeah yeah. Preach to the introvert about the downfalls of introversion... It's not some mystery to me. =P I've always been the sort who enjoys urban spelunking and blending in with the crowd--a bit of that invisibility fantasy thing, coupled with my love of exploration--but I will admit I certainly crave the company of a select few companions, from time to time. It's nice to have folks around with common interests. Guess we'll see where things go. =P

+Goldie Tamamo I don't think you need to worry about ever having to fight any laws or taboo against you becoming whatever type of tranhuman that you want. And there will be different types and they'll be given different categories at the time. But the reason you won't have to worry, is that there won't be any way to stop you. Just like with my reference to anybody and everybody being able to create their own advanced weapons: There won't be any way to stop them. There isn't any way to stop software piracy now, and the entire field of transhumanism (and weapons, and everything else) will be reduced down to software for your advanced 3D printer. You'll just print whatever mods you want to do to yourself, from a file loaded into the printer from the internet. And with things like Neural Link coming along, you'll be so smart that it'll be nothing to figure out how to do it and integrate them into your body flawlessly. Governments aren't even going to be around in the long run. Without "need" in the world (food, shelter, water, etc) they'll become almost completely redundant. Redundant institutions and organizations always stop existing, with no exceptions. You may have some local city councils, but that'll be about it. The future is so radically different from what we experience today, that it will indeed be a paradigm shift away from governments. They simply won't be necessary anymore, for anything. But I doubt there will be any transhumans who will be able to completely forego interacting with others. All things have limits, and transhumanism is no different. It can't change your psychology, and if you go long enough in isolation you will go insane, no question. Well there is a caveat to that, you could change your psychology, just as people do now with different types of legal and illegal drugs, but you'll be worse off for it, not better. So much so that I'd say that to do so would largely negate the gains you'd received from becoming transhuman. I doubt this is possible, but if you could "turn off" the need to be around other conscious self aware beings, you wouldn't be able to stop from becoming something you'd never want to be. Thus, few will ever do it. And those that do, will likely eventually need to seek help from the transhuman psychologists that will doubtless exist, just as we have vanilla human psychologists now. Because in turning off certain aspects of your psyche, you inevitably turn off other aspects that are integrated into it. In short you'd become less, not more. And the others who didn't do that, would have very large and very distinct advantages over you, since you'd no longer be capable of really understanding why they did the things that they did. They'd ascend to greater heights while you'd be left behind. Eventually. And that's just one part of the psyche, that desire to have associations and interactions with other people. You could extend that to any other part of the psyche, say fear for example. Or anger. Or... whatever. You go turning those off, and it may end up resulting in your demise. Thus, you'll never be able to really be just cut off from society. You may be able to do it for a while, but you'll come back with a brand new appreciation for it, and realize what you've been missing. I can say this from personal experience. Its also well documented in prisoners.

+jigga jaw You seem to have quite misconstrued: I don't 'demand' anything. I'm quite used to being an outcast. But I'd at least assume you'd prefer a friendly working relationship to a tyrannical one that necessitates that sort of person be an enemy. I'd prefer to negotiate with my fellow man than have to subversively overthrow my way out of being a plain jane human. I would however 'suggest' --not demand, just suggest --that being diplomatic with those different to you, and at minimum, being aware of their existence, may behoove you in the long-term. The Albert Weskers and Alexia Ashords of the world, who would turn themselves into something other-than-human without a second thought, are always going to be out there, for better or worse. It's at least practical that you know it and keep it in mind. Not everyone who is human now, will remain human later, just because it's accepted that most intend to. Some of us quite hate humans and hold a grudge--hypocritical as that may seem. I wouldn't count myself among them at this point, but there was that point in life where I was an utter misanthrope. Anyways, it sounds like you have quite the concern with wild pokemon running around in the grass. I would consider engineering them to be capable of human diplomacy, or else invest in the production of ultra balls. ;P

+Goldie Tamamo Well I notice that you would demand that others accept you for your future transhuman choices. And that's fine, as long as you're always accepting of their choices as well. Because while I know there will be many people who will be like you'll be in the future, there will also be those like me who will be transhuman for sure, but largely they'll stick to the human form. This has a ton of advantages, not the least of which is standarization for ease of use in a myriad of scenarios and applications. But it probably won't be that cut and dry, it will likely be much more fluid. You're a fox one day, and a human the next day. I tend to identify more with machines but that's just personal preference. As for weapons being a point of pride, I'm not sure that's really the common mentality with weapons. Its really more along the lines of defense from... well evil. They may be fun to play with in controlled settings, but beyond that you really only keep them around for more of a "Don't start nothin, won't be nothin' type mentality. An armed society, is a polite society as the old adage goes. For eating them from the inside, you'd have to deal with their transhuman immune system first, which really just takes the fight to a different arena. If you have an enemy that you have to destroy, its probably best not to go that route cause now you're basically into the realm of computer hacking (of a sort) and its a lot easier to just destroy their physical form with advanced weapons and efficient robots. Talking about this makes me realize the bio kill machines really won't stand a chance, due to an innate lack of intelligence. If you give them too much intelligence, they're just going to turn on you. They'll say "And why exactly, am I risking my life for you?" So they'll have to be on the dumber side, which makes them no match for a transhuman. Since transhumans will be far smarter than any vanilla human of today. The "monsters" would just be too far outmatched. When it comes to these dumb animal monsters (like in resident evil for example) I was actually thinking of a somewhat different scenario. A scenario in which for some reason, even in a transhuman world, there were still regular old humans who were perhaps born in a situation where they just weren't transhuman. Take the Amish for example. We've got no right at all to tell them how to live, thus we must respect their choice to remain "vanilla" human. But that won't stop the killbeast that roams the forest cause it got loose or... who knows what the situation might be. But its out there now (maybe more than one) and the Amish are now subject to its whims. Or other vanilla humans, who may be born in a situation where they're just vanilla. Even if it is only for 20 years or so before they eventually receive all manner of upgrades. This could be in the far future, where many of the transhumans have long since left the planet, yet their normal human kin remain on the planet just living the way that they always have. Oh but now they've got the occasional monster to deal with, which is not cool at all. Thus they should avail themselves of the powerful weaponry needed to kill it.

+jigga jaw One thing you're going to learn is that some people are of a disposition to watch human activity from a distance, without becoming overly involved--and some of those types are curious about exploring the nature of beyond-human existence. The talking-with-animals, walking-with-animals sort. Not everyone cares all that much about the human image, and some people are physically attracted to alien features, whether they like it or not (I have a particular soft spot for fox whiskers). Now, if we wanted to be boring, we could try to correct all those aesthetic interests and keep everyone 'normative', but the far less tyrannical approach is probably to facilitate these niche interests--within reason--when they become readily achievable, rather than creating some kind of taboo around it. The sooner you learn to get along with this tiny portion of humanity, or at the very least learn how to deal with them peaceably, the better it'll be for everyone. Think of us as that little crack in the dyke that could cause everything to go to shit if not adequately addressed soon enough with some diplomacy. Basically I'd like to be more fox-like, because I follow the myths about the gods that aren't 100% human-like. Uka-no-mitama, or Inari, for instance. Or perhaps Zeus would be one you would be more likely to get--he got up to a lot of shape-shifting debauchery with human women in animal forms. I suspect I would try to be a bit more ethical than Zeus, however... My intentions with Neuralink or its equivalent would be to connect myself to a familiar-body, and be able to control both a human-like and quadruped-animal body, simultaneously, or something like that. I can think of a lot of fun permutations of being able to add things to my neural network, everything from growing additional tails, to merging with other beings cognitively and/or physically to appreciate the experience of symbiosis into a collective, to being able to be in multiple places at once, and then some. If 'weapons' are your concern, there's always just infesting people and eating the ones you don't like, from the inside out (go Team Zerg =P). I think it might be wise not to turn weaponizing technology into a matter of pride, though--some people are just going to be a lot more inventive than you, about how they'd hurt people, and I think there's probably more productive ways to compete with our ideas... And I say this as someone who is just a tiny bit of a gun hobbyist, too. I think an interest in weapons is not a problem in and of itself, but an excessive pride for weaponry might be.

+Goldie Tamamo Well given the topic, I assumed everyone had imagined the resident evil scenario when they see a video like this. So I didn't think it would need much explanation. You want to become a monster in the vein of what I'm referring to? lol. You're probably one of a very few then. Most transhumanists I talk to, want to still look human. Why become something (physically at least) that nobody would want to interact with? I want to look similar to the way I do now, but be so modified internally that I'd be what the ancient greeks would've called a god. I mean at that point, you can have the perfect human form. It'll be real nice when everyone is beautiful. I'm in the U.S, and as such I definitely side with the people being able to keep and bear arms. Goes a long way towards fending off tyranny. But then again, 30 years from now, you'll be able to make your own plasma weapons so the unintelligent monsters of Resident evil would just be target practice. Target practice for your advanced robots, since there would be no need for you to fight these "monsters" yourself. And if you did, the monster is going to have its work cut out for it, trying to take down a transhuman, even one that still largely has the same human form as people do now. You'd be able to beat up on the Terminator from those movies like it was nothing. But yes in the future, no country will be able to stop people just producing their own highly advanced weaponry, right in the comfort of their own home. With the Neural Link, you'll just download everything there is to know about weapons, and then design your own printer from scratch if you need to, to print them. Governments are just going to have to get used to people keeping and bearing arms, which will make those governments much more receptive to the will of the people. Its a good thing. Oh they can try to ban the file from circulating around the internet, but you see how far that gets them even now. Plus there's always free and open source software that someone will write and put out there, just cause they disagree and they want people to build and keep their own weapons. Little pussies need not apply, they can just opt not to create weapons.

​+jigga jaw No... you? I... don't... really have to do anything of the sort? Perhaps a little more clarity when talking about 'the monsters' is in order, in the future, since your average human being is not yet a mind-reader, and you provided like, zero context to your comment. But sure, designer killbeasts. I gotcha. Resident Evil is practically a part of my personal mythology. Weaponized bioengineering is a given, the question is just whether you're on the side of giving people the 'guns', or rounding them up and keeping them under... 'gubbernment'... control. Considering I intend to become one of those 'monsters', at the earliest reasonable opportunity, you'd best hope that at least some of them 'are' nice.

+Goldie Tamamo If you're going to be transhuman you're going to have to stop making assumptions about people. I'm talking about people who eventually create "custom" animals out of this stuff. You know they will. And some of them probably won't be very nice.

Oh ok, so THIS is "where are" the human supremacists are going to come from. I get it now.

I'm personally hoping to be part of the squad of furry-synths that cull all the screaming normies and put them in a daycare where they won't gun each other down over their melanin concentration or shape of their genitals, or something. Lord knows an AI-dominion is probably not the stupidest way the human species could abort itself, at this point.

Perhaps they'll invent a cure for your cynicism. But hey, maybe if you pray to the concept of 'freedom' hard enough, some bald eagles will swoop down out of the sky with expensive new military grade armaments and sacrifice the younger generation in order to undo this decadent Satanic filth. ( ͡~ ͜ʖ ͡°)

If you keep standing there with your mouth agape, it will rain, and you will drown.

You would honestly be surprised with the number of people who want tails. It's like asking why people would want to be taller, or be blonde, or have double-D's, or get a face-lift to look like Michael Jackson. Let people be individuals, damnit. Don't just talk about freedom when it's convenient and then shit your pants and opt we all file into your padded cell with you when you don't see the appeal.

Keep dreaming chief.

Hmmmm. Could this be because: A.) Talk is cheap and resource distribution isn't B.) *CONSPIRACY!!!*

They were caught up in whether they could, without stopping to think if they should, eh?

Poe's law is on full alert. -.-

Nah, they just spin it that we're the devil's minions looking to debase humanity, as if humanity is a monolithic entity. They're always complaining, their shrill cries are just so ubiquitous at this point that people tune them out.

Now is when the unfettered optimists and the unfettered cynics alike cross paths and shit their collective trousers, while the down-to-earth pragmatists do the boring work to make some of it squeeze through the rectum of realistic limitation and probability. Also, some of the furries are 'also' customizable pokemon AND super humans. In fact, fear the coming Inkling conquest of humanity, as well.

*makes the scheming furry jew meme*

Nine-tails, and regenerating synth-steel claws, and veins coursing with the echoes of the old blood. A handful of the stolen fire of the Olympians, and maybe a few whiskers off of God's beard, for good measure. Perhaps we can even graft pandora's box to your ass. I believe the term you're looking for is 'chimera-making' territory, by-the-by.

Imagine that you wake up one day with your identity saved on the cloud, able to think through a computational matrix in a super-computer, and you can just elect to have a body when it suits you, and voluntarily 'respawn' when you have a horrific discombobulating accident, rather than lying about in a pre-coma state of agony while waiting for medical professionals to find you and retrieve you for an extended hospital stay. See, we can do the speculative science-fiction conspiracy game all day, but something as simple as getting maimed in an accident is always just around the corner, with or without the mad science. One of these futures at least has a solution for the 'broken everything in muh body' problem, while neither has a solution for your invisible bogeyman mastermind with devices on control over the populace. If the Knights Templar worshipers of Baphomet Illuminati Freemason Superjew ghouls with access to advanced alien tech truly do exist, you're pretty much equally fucked in either reality.

You. Get down on the ground now and shed all your possessions, and work for your fellow man's base survival. No? That's what I fucking thought. Now excuse me while I wait with baited breath for a tail.

​+His Favorite Oh, we simply assumed they sprouted out of the ground like Orcs from Isengard, like the rest of the monstrous humanoid races in the 3.5e Monster Manual. *rolls eyes* Thy bare skin-having days are nigh, prepare for furry man-dog-fucking critter supremacy, smoothies...

Tell us more about which ones you feel are the good and which ones are the evil ways. Your hot take is requested. ( ͡° ʖ̯ ͡°)

Oh yeah?! Well *my* DNA is Krishna!!!

... FURRY. POWER. *jackboot noise commences*

+P C BARR The Noah story was plagiarized from even older stories, chief. Sorry to ruin your childhood.

Welcome to being a human being--you have this lovely faculty that leads you to believe you have this thing called 'free-will' and 'decision-making capacity', along with the ability to implement tools and alter your environment to better suit your needs and desires. If you have a problem, time-travel back and abort homo erectus or something.

Yes. Only less lame and whiny. Hopefully.

Chris, you'll never understand... it's magnificent.

Those damn oversea scammer, they manage to encrypt my DNA, they leave me 36h to give them 299.99$ or I'm not getting my DNA back...

this will probably destroy human race not improve!!

playing gods is really wise thing...these people cant even provide food for himself and they are playing game like this get a real job folks u have to much time to think....

The big pharma companies would have to give up their lucrative dependency on chemotherapy income. Time and again we've been told about a cure for this or that cancer, and that's the last you hear of them. This is the case for all sorts diseases that pharma companies need the sick to be reliant on their products that don't cure you and don't fully address the symptoms. Like others commenting here, those crispa kits should be banned. I don't know if this is true, but I heard that by modifying a gene there develops a knock on effect elsewhere. As such, laws should be passed so that unqualified people are not allowed access to such technology. What if a virus mutates that could harm other humans? As usual, there is much hubris concerning advancements in science. If half as much effort was put into how humans live we may have a better society. Imagine being cured of a disease only to face a life of poverty because automation and AI has taken your job. And the level of basic income being toyed with by the UK is just 60 quid a week, lower even than job seekers allowance.

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